The Basics
GI Calm delivers gut-building botanical extracts to boost the body’s ability to soothe, repair and regenerate the lining of the esophagus and the intestinal tract.
The antimicrobial properties of zinc-camosine and Vitamin C are combined with three key gut building botanical extracts known for their protective qualities: mastic (derived from tree resin), DGL (deglycyrrhizinated licorice) and methylmethionesulfonium (from raw cabbage)
Providing a safe and natural approach to heartburn and indigestion, these nutrients move quickly and efficiently to the stomach and intestines for long-term protection and improved gastric health.
How to take it
Take 2 capsules twice daily, between or with meals or as directed by your health care practitioner.
Contents
60 capsules
Heartburn and Indigestion
Balance your upper GI tract, overcome heartburn and indigestion, see Heartburn Bundle
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Product Ingredients
GI CALM

Directions
As a dietary supplement, take 2 capsules twice daily, between or with meals or as directed by your health care practitioner.
Formulated to exclude wheat, yeast, soy, gluten, eggs, dairy, artificial colors, flavors, sugars or preservatives.
Store tightly closed in a cool, dry, dark place. Natural color, size and shape may vary between lots. Keep out of the reach of children
Manufactured in an NSF certified GMP registered facility.
Research
GI CALM
In vitro and in vivo activities of Chios mastic gum extracts and constituents against Helicobacter pylori.
Paraschos S, Magiatis P, Mitakou S, Petraki K, Kalliaropoulos A, Maragkoudakis P, Mentis A, Sgouras D, Skaltsounis AL.
Antimicrob Agents Chemother. 2007 Feb;51(2):551-9. Epub 2006 Nov 20.
PMID:17116667[PubMed - indexed for MEDLINE]
Free PMC Article
Related citations
Zinc L-carnosine protects against mucosal injury in portal hypertensive gastropathy through induction of heat shock protein 72.
Mikami K, Otaka M, Watanabe D, Goto T, Endoh A, Miura K, Ohshima S, Yoneyama K, Sato M, Shibuya T, Segawa D, Kataoka E, Yoshino R, Takeuchi S, Sato W, Odashima M, Watanabe S.
J Gastroenterol Hepatol. 2006 Nov;21(11):1669-74.
PMID:16984587[PubMed - indexed for MEDLINE]
Related citations
Zinc L-carnosine protects colonic mucosal injury through induction of heat shock protein 72 and suppression of NF-kappaB activation.
Odashima M, Otaka M, Jin M, Wada I, Horikawa Y, Matsuhashi T, Ohba R, Hatakeyama N, Oyake J, Watanabe S.
Life Sci. 2006 Nov 10;79(24):2245-50. Epub 2006 Aug 2.
PMID:16949620[PubMed - indexed for MEDLINE]
Related citations
Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes.
Mahmood A, FitzGerald AJ, Marchbank T, Ntatsaki E, Murray D, Ghosh S, Playford RJ.
Gut. 2007 Feb;56(2):168-75. Epub 2006 Jun 15.
PMID:16777920[PubMed - indexed for MEDLINE]
Free PMC Article
Related citations
Anti-Helicobacter pylori flavonoids from licorice extract.
Fukai T, Marumo A, Kaitou K, Kanda T, Terada S, Nomura T.
Life Sci. 2002 Aug 9;71(12):1449-63.
PMID:12127165[PubMed - indexed for MEDLINE]
Related citations
Antioxidant effects of herbal therapies used by patients with inflammatory bowel disease: an in vitro study.
Langmead L, Dawson C, Hawkins C, Banna N, Loo S, Rampton DS.
Aliment Pharmacol Ther. 2002 Feb;16(2):197-205.
PMID:11860402[PubMed - indexed for MEDLINE]
Free Article
Related citations
Bactericidal activity of Pistacia lentiscus mastic gum against Helicobacter pylori.
Marone P, Bono L, Leone E, Bona S, Carretto E, Perversi L.
J Chemother. 2001 Dec;13(6):611-4.
PMID:11806621[PubMed - indexed for MEDLINE]
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Helicobacter pylori eradication: are there alternatives to antibiotics?
Gaby AR.
Altern Med Rev. 2001 Aug;6(4):355-66. Review.
PMID:11578252[PubMed - indexed for MEDLINE]
Free Article
Related citations
Mastic gum kills Helicobacter pylori.
Huwez FU, Thirlwell D, Cockayne A, Ala'Aldeen DA.
N Engl J Med. 1998 Dec 24;339(26):1946. No abstract available.
PMID:9874617[PubMed - indexed for MEDLINE]
Free Article
Related citations
[Clinical effect and an analysis of the mechanism of action of vitamin U (S-methylmethioninesulfonium chloride) in peptic ulcer of the stomach and duodenum].
Tsimmerman IaS, Golovanova ES.
Ter Arkh. 1976;48(3):29-35. Russian. No abstract available.
PMID:1006535[PubMed - indexed for MEDLINE]
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[Therapeutic effectiveness of methylmethioninesulfonium chloride (vitamin U) in patients with chronic enterocolitis].
Trusov VV, Vakhrushev IaM.
Vrach Delo. 1974 Dec;(12):78-82. Russian. No abstract available.
PMID:4446538[PubMed - indexed for MEDLINE]
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[Methylmethioninesulfonium chloride (vitamin U)].
Tumanov VA, Chekman IS.
Farm Zh. 1973 Nov-Dec;28(6):82-3. Ukrainian. No abstract available.
PMID:4792463[PubMed - indexed for MEDLINE]
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